For this reason, people with liver illnesses or people who chronically consume large amounts of alcohol should be particularly careful when taking acetaminophen and should consult their doctor prior to taking acetaminophen compounds. If the liver is already damaged because of infection, alcohol abuse, or other illness, a person may be more susceptible to damage from acetaminophen overdose. Too much acetaminophen can overwhelm the way the liver normally functions. Illness from acetaminophen overdose is caused primarily by liver damage.Īcetaminophen is primarily metabolized by the liver. For this reason, it is absolutely necessary that acetaminophen poisoning be recognized, diagnosed, and treated as early as possible. Indeed, NAC can prevent liver failure if given early enough. It is most effective when given within eight hours of ingesting acetaminophen. The antidote to acetaminophen overdose is N- acetylcysteine (NAC). If the damage is severe, a liver transplant may be necessary in order to save someone’s life. Acetaminophen is in Actifed, Alka-Seltzer Plus, Benadryl, Co- Gesic, Contac, Excedrin, Fioricet, Lortab, Midrin, Norco, Percocet, Robitussin, Sedapap, Sinutab, Sudafed, TheraFlu, Unisom PM Pain, Vick's Nyquil and DayQuil, Vicodin, and Zydone.Īcetaminophen in overdose can seriously damage the liver. It is also found in many other over-the-counter medications and in prescription drugs.

Unless otherwise directed by your care provider, the usual maximum recommended dose is 3 grams in 24 hours.Īcetaminophen is the active ingredient in Tylenol. However, if taken in excess amounts (overdose, whether on purpose or by accident), acetaminophen can cause life-threatening illness. Over many years, it has been used countless times by many people, and it has proven to be a safe and effective medication. It is used for the treatment of pain and to lower fever. Acetaminophen (Tylenol) Poisoning OverviewĪcetaminophen is one of the most common medications found in households.

Paracetamol antidote